How does our body cope with stress of viral infections?
researchers said nitric oxide appears to be fundamental in protecting the overall redox system.Author : Divyanshi Soni
UK researchers who are analyzing the effects of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus causing Coronavirus, on the human body have provided few measures to deal with the stressful situations that occurred due to uncontrollable spreading of the virus.
Now, the team of physicians, chemical biologists, and human nutritionists is researching Covid-19, considering it more than just a disease affecting the lungs. They have been reviewing it as how the whole body deals with the stress caused by the virus and are viewing it through the lens of electron exchange ‘redox’ processes.
Their analysis which has been published in the Journal Antioxidants and Redox Signalling revealed the major measures to cope with the stress of viral infections.
First, Nutrition is most important in maintaining the necessary redox balance. It is nutrition that provides the power and flexibility to one’s metabolism to fight against the damaging effects of viral infections on cells and tissues.
Second, Gasotransmitters, are the small molecules that use blood as a communication highway. These molecules use circulating blood to inform the organs have to respond to the mixture of stresses experienced by the human body in the best way. Taking the latest example, these would help to ramp up the metabolism in the liver to deal with the Coronavirus infection.
The researchers said nitric oxide appears to be fundamental in protecting the overall redox system.
Martin Feelisch, Professor of Experimental Medicine and Integrative Biology at the University of Southampton said, “Arriving at a better understanding of how the body deals with different stress while maintaining an appropriate redox balance would put us in a better position to treat patients acutely, protect the rest of the population and control disease spread.”
She added, “While the current vaccination success story is encouraging, emerging virus mutants show the threat continues, and we need to be better prepared in the future.”